This is the first report of mosquitoes infected with CHIKV in Iran. The high-throughput screening method here presented can be proposed as a novel epidemiological surveillance tool to identify circulating arboviruses and to support preparedness to an epidemic in animals and humans.
The authors of this study demonstrate Flavivirus-dependent differences in the interaction with monocyte-derived dendritic cells. These may play a role in pathogenesis but appear to only partially reflect the expected species tropism.
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